Product Overview

Cholib contains two active ingredients:

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  Fenofibrate (145 mg) – reduces triglycerides and raises HDL cholesterol.

  
  


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  Simvastatin (40 mg) – reduces total cholesterol and LDL (bad) cholesterol.

  
  

It is used in adults with mixed dyslipidemia who are at high cardiovascular risk and whose lipid levels cannot be adequately controlled by statin alone or by diet and lifestyle.

How to Use

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  Dosage: One tablet once daily.

  
  


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  Timing: Take with food in the evening.

  
  


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  Do not crush or chew the tablet.

  
  


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  Continue your low-cholesterol diet during treatment.

  
  

Do Not Take Cholib If You:

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  Are allergic to fenofibrate, simvastatin, or any ingredients in the tablet.

  
  


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  Have liver disease, gallbladder disease, or pancreatitis (unless due to high triglycerides).

  
  


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  Are pregnant, breastfeeding, or female of childbearing potential not using contraception.

  
  


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  Are taking medicines that strongly interact with simvastatin (e.g. itraconazole, ketoconazole, HIV protease inhibitors, gemfibrozil, etc.).

  
  

Precautions – Talk to Your Doctor If You:

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  Have kidney, liver, or thyroid issues.

  
  


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  Are over 70 years old.

  
  


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  Have unexplained muscle aches or a history of muscle problems, especially with statins or fibrates.

  
  


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  Drink excessive alcohol.

  
  


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  Have diabetes, low albumin, or low thyroid hormone (hypothyroidism).

  
  


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  Are taking other medications like anticoagulants, immunosuppressants, or other lipid-lowering drugs.

  
  

Monitoring During Treatment

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  Your doctor will perform blood tests to monitor liver, kidney, and muscle enzymes before and during treatment.

  
  

Possible Side Effects

Common (up to 1 in 10):

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  Headache

  
  


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  Digestive symptoms: nausea, diarrhea, abdominal pain

  
  


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  Increased liver enzymes

  
  

Uncommon (up to 1 in 100):

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  Muscle cramps or weakness

  
  


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  Skin rash or itching

  
  


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  Dizziness or fatigue

  
  


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  Gallstones

  
  


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  Elevated creatinine or urea in blood

  
  

Rare but serious:

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  Muscle damage (rhabdomyolysis) – a medical emergency

  
  


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  Liver inflammation or jaundice

  
  


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  Pancreatitis

  
  


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  Severe skin reactions (e.g., Stevens-Johnson syndrome)

  
  


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  Interstitial lung disease

  
  

Seek medical help immediately if you experience:

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  Muscle pain, weakness, or tenderness

  
  


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  Yellowing of the skin or eyes

  
  


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  Dark-colored urine

  
  


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  Severe allergic reactions (e.g., facial swelling, breathing difficulty)

  
  

Ingredients

Active ingredients:

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  Fenofibrate 145 mg (as fenofibric acid)

  
  


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  Simvastatin 40 mg

  
  

Other ingredients (excipients):

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  Lactose monohydrate

  
  


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  Microcrystalline cellulose

  
  


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  Sodium starch glycolate

  
  


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  Pregelatinized starch

  
  


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  Sodium lauryl sulfate

  
  


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  Magnesium stearate

  
  


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  Coating: hypromellose, titanium dioxide (E171), macrogol 400, iron oxide yellow (E172)