Jadenu 180 mg Film-Coated 30 Tablets

Product Description:

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  JADENU is an iron chelator indicated for the treatment of chronic iron overload due to blood transfusions in patients 2 years of age and older.

  
  


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  JADENU is indicated for the treatment of chronic iron overload in patients 10 years of age and older with non-transfusion-dependent thalassemia (NTDT) syndromes, and with a liver iron (Fe) concentration (LIC) of at least 5 mg Fe per gram of dry weight (Fe/g dw) and a serum ferritin greater than 300 mcg/L.

  
  

How to use:

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  Transfusional Iron Overload: Initial dose for patients with estimated glomerular filtration rate (eGFR) greater than 60 mL/min/1.73 m2 is 14 mg per kg (calculated to nearest whole tablet or nearest whole sachet content for granules) once daily.

  
  


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  NTDT Syndromes: Initial dose for patients with eGFR greater than 60 mL/min/1.73 m2 is 7 mg per kg (calculated to nearest whole tablet or nearest whole sachet content for granules) once daily.

  
  

Caution & Warnings:

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  Acute kidney injury, including acute renal failure requiring dialysis and renal

  
  


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  Tubular toxicity including Fanconi syndrome

  
  


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  Hepatic toxicity, including failure

  
  


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  Gastrointestinal hemorrhage

  
  

Side Effects:

• Diarrhea, vomiting, nausea, abdominal pain, skin rashes, and increases in serum creatinine.

Ingredients:

• Deferasirox 180Mg.