1. What Jusprin 81 is and what it is used for

What the medicinal ingredient is:
Acetylsalicylic Acid (aspirin)
What dosage forms it comes in:
Jusprin 81 comes as enteric-coated tablets, 81 mg.
What the medication is used for:
- Jusprin 81 is for doctor-supervised long-term preventive therapy.
- Jusprin 81may help save your life if you think you are having a heart attack.
What it does:
Jusprin 81 is for doctor-supervised long-term preventative therapy.
USE DURING A HEART ATTACK
If you think you are having a heart attack, call hospital emergency department
immediately then, chew or crush and swallow two Jusprin 81 tablets. It is important to
chew or crush the product, to ensure this medicine works quickly. Then get to a hospital
immediately for medical attention.
Inform the emergency services / hospital that you have taken Jusprin 81.
Taking Jusprin 81, at the first signs and symptoms can reduce your risk of dying from a
heart attack.
The signs and symptoms of a heart attack include:
• uncomfortable pressure, fullness, squeezing or pain in the centre of the chest that
lasts more than a few minutes, or goes away quickly and comes back
• pain that spreads to the shoulders, neck or arms
• chest discomfort with light headedness, fainting, sweating, nausea or shortness of
breath.
Chest pain is the most common symptom in both sexes, but women may also experience
other symptoms such as unusual fatigue that gets worse with activity, difficulty of
breathing, heartburn/nausea and /or vomiting unrelieved by antacids, tightening and pain
in the chest that may extend into the neck, jaws and shoulders, general feeling of
weakness, paleness, sweating)
At the hospital, the doctor will then recommend appropriate therapy.
2. Before you take Jusprin 81
When it should not be used:
DO NOT TAKE if you:
• are allergic to aspirin, salicylates, non-steroidal anti- inflammatory drugs
(NSAIDs)/pain relievers/fever reducers or other ingredients in the product
• have an ulcer, history of ulcers or are prone to bleeding
• have active or severe liver or kidney disease or congestive heart failure
• have a history of asthma caused by salicylates or other NSAIDs
• are using methotrexate at doses of 15 mg/week or more
• are in the last trimester of pregnancy because it may cause problems to the unborn
child or complications during delivery.
Warnings and Precautions
Your doctor will have asked you many questions about your health, lifestyle, and
medications before recommending Jusprin 81.That is why it is very important that you
tell your doctor all such information. If you have forgotten to tell your doctor about any of
the following, call your doctor or pharmacist before you take this medicine (or any
medicine):
• asthma, high blood pressure, heart disease, gout or other serious conditions
• age 60 years or older
• stomach problems such as heartburn
STOMACH BLEEDING WARNING: contains a NSAID which may cause severe
stomach bleeding
• impaired liver/kidney or impaired cardiovascular circulation (renal vascular disease,
congestive heart failure, volume depletion, major surgery, sepsis or major
hemorrhagic events)
• history of blood clotting defects
• severe anemia
• severe glucose-6-phosphate dehydrogenase (G6PD) deficiency
• are trying to conceive, pregnant or breast-feeding or
• will be having surgery in five to seven days.
CAUTION: Contains enough drug to seriously harm a child.
KEEP OUT OF REACH AND SIGHT OF CHILDREN. DO NOT GIVE to
children/teenagers less than 18 years of age who have chicken pox or cold/flu symptoms
before a doctor is consulted about Reye’s Syndrome, a rare but serious illness reported
to be associated with aspirin.
Interactions with this medication
Tell your doctor if you are taking any prescription or nonprescription drugs including
blood thinners, acetaminophen, anticonvulsants, anti-diabetic/arthritis/gout medicines,
digoxin, glucocorticoids, methotrexate, selective-serotonin re-uptake inhibitors (a type of
antidepressant), diuretics, ACE inhibitors (medication for high blood pressure), or if you
are having 3 or more alcoholic drinks per day.
Do not use ibuprofen if you are taking Jusprin 81 for preventive therapy without talking
to a doctor or pharmacist. NSAIDs (i.e. ibuprofen or naproxen) may interfere with the
preventive benefits of of Jusprin 81.
3. How to take Jusprin 81
Always take Jusprin 81 exactly as your doctor has told you to. You should check with
your doctor or pharmacist if you are not sure.
Usual dose:
DIRECTIONS (Adults ≥ 18 years): For doctor-supervised long-term preventive
therapy: 1 to 4 tablets daily, depending on your doctor’s instructions. You should take
this medicine at the same time every day. This will help you to remember to take your
medication. For maximum effectiveness, it is very important to take Jusprin 81 every day
as directed by your doctor. Do not take more tablets than your doctor recommends. Your
doctor may tell you to take Jusprin 81 with other medications; he or she may also tell
you to eat special foods, exercise or take other steps to safeguard your health. Jusprin
81 tablets have a special enteric coating, which allows them to pass undissolved through
the stomach and into the intestine. By dissolving in the intestine rather than the stomach,
the risk of stomach upset is reduced. Therefore, to maintain this protection, the tablets
should not be crushed or broken.
During a heart attack: Call hospital emergency department immediately, then, crush or
chew 2 tablets.
Can I continue to take Jusprin 81 for relief of headache, fever or arthritis pain?
Jusprin 81 is specially designed for doctor supervised long-term preventive therapy. It is
a smaller dose than you would need to take for a headache or other types of pain and is
unlike other pain reliever products such as acetaminophen or NSAIDs e.g., ibuprofen,
naproxen. Ask your doctor or pharmacist about other aspirin products available (or other
pain relievers such as acetaminophen, ibuprofen, naproxen or salicylates) and the
correct dosage for the relief of your headache, fever or arthritic pain.
Always consult with your doctor or pharmacist before taking other medications.
Overdose:
If you have taken too much Jusprin 81, contact your healthcare professional or hospital
emergency department immediately, even if there are no symptoms.
Missed dose:
If you forget to take your medication, take it when you remember.
But do not take extra medication to compensate for a missed dosage unless instructed
by your doctor.
If you have any further questions on the use of this product, ask your doctor or
pharmacist.
4. Possible side effects
Like all medicines, Jusprin 81 may occasionally produce unwanted side effects. You
should call your doctor if you experience: nausea, vomiting; stomach irritation, or pain; if
you notice that you are ‘bruising’ more easily than you were before starting a daily dose
of Jusprin 81. Regular daily use of alcohol while on Jusprin 81 daily therapy may
increase your risk of developing gastrointestinal bleeding.
This is not a complete list of side effects. For any unexpected effects while taking
Jusprin 81, contact your doctor or pharmacist.
Serious side effects, how often they happen and what to do about them
Stop use and call your doctor if you experience an allergic reaction (skin rash, hives,
itching, swelling of eyes, face, lips, tongue, or throat, wheezing or breathing difficulties);
stomach bleeding (feel faint, bloody vomit, vomit that looks like coffee grounds, bright red
blood in stools, black or tarry stools, stomach pain that does not get better); loss of
hearing, ringing or buzzing in ears, or bleeding.
Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist. This includes any possible
side effects not listed in this leaflet. 
5. How to store Jusprin 81
- Keep out of the reach and sight of children.
- Do not take Jusprin 81 after the expiry date which is stated on the carton and the inner
label.
- Store below 30°C, in a dry place.
After opening: use within 30 days.
- Do not take Jusprin 81 if you notice any visible sign of deterioration.
- Medicines should not be disposed of via wastewater or household waste. Ask your
pharmacist how to dispose of medicines no longer required. These measures will help
to protect the environment.