Kerendia Finerenone 10 mg Tablets 28

Product Description:

• Finerenone is a nonsteroidal, selective antagonist of the mineralocorticoid receptor (MR) which is activated by aldosterone and cortisol and regulates gene transcription.
• Its binding to the MR leads to a specific receptor-ligand complex that blocks recruitment of transcriptional coactivators implicated in the expression of pro-inflammatory and pro-fibrotic mediators.

How to use:

• The recommended target dose is 20 mg finerenone once daily.
• A missed dose should be taken as soon as the patient notices, but only on the same day. The patient should not take 2 doses to make up for a missed dose.

Caution & Warnings:

• Hypersensitivity to the active substance or to any of the excipients.
• Concomitant treatment with strong inhibitors of CYP3A4, e.g.,
  itraconazole, ketoconazole, ritonavir, nelfinavir, cobicistat, clarithromycin,telithromycin,nefazodone.
• Addison's disease
• Hyperkalaemia

Ingredients:

• Finerenone