Product description:

Co-amoxiclav 400/57mg/5ml Powder for Oral Suspension is indicated for the treatment of the following infections in adults and children:

• Acute bacterial sinusitis (adequately diagnosed)


• Acute otitis media


• Acute exacerbations of chronic bronchitis (adequately diagnosed)


• Community acquired pneumonia


• Cystitis


• Pyelonephritis


• Skin and soft tissue infections in particular cellulitis, animal bites, severe dental abscess with spreading cellulitis.


• Bone and joint infections, in particular osteomyelitis.

How to use:

• For adults and children ≥ 40 kg, this formulation of Co-amoxiclav 400/57mg/5ml Powder for Oral Suspension provides a total daily dose of 1750 mg amoxicillin/250 mg clavulanic acid with twice daily dosing and 2625 mg amoxicillin/375 mg clavulanic acid with three times daily dosing, when administered as recommended below.


• For children < 40 kg, this formulation of Co-amoxiclav 400/57mg/5ml Powder for Oral Suspension provides a maximum daily dose of 1000-2800 mg amoxicillin/143-400 mg clavulanic acid, when administered as recommended below.


• If it is considered that a higher daily dose of amoxicillin is required, it is recommended that another preparation of Co-amoxiclav 400/57mg/5ml Powder for Oral Suspension is selected in order to avoid administration of unnecessarily high daily doses of clavulanic acid .


• The duration of therapy should be determined by the response of the patient.


• Some infections (e.g.osteomyelitis) require longer periods of treatment.


• Treatment should not be extended beyond 14 days without review .

Caution & Warnings:

• Before taking this product, tell your doctor or pharmacist if you are allergic to amoxicillin or clavulanic acid; or to penicillin or cephalosporin antibiotics; or if you have any other allergies.


• This product may contain inactive ingredients, which can cause allergic reactions or other problems.


• Talk to your pharmacist for more details.


• Before using this medication, tell the doctor or pharmacist your medical history, especially of: liver disease (including liver problems caused by previous use of amoxicillin/clavulanic acid), kidney disease (such as requiring dialysis), a certain type of viral infection (infectious mononucleosis).


• Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).


• This product may cause live bacterial vaccines (such as typhoid vaccine) to not work as well.


• Do not have any immunizations/vaccinations while using this medication unless your doctor tells you to.


• During pregnancy, this medication should be used only when clearly needed.


• Discuss the risks and benefits with your doctor.


• This medication passes into breast milk.


• Consult your doctor before breast-feeding.

Side effects:

Stop using this medicine and call your doctor at once if you have a serious side effect such as:

• diarrhea that is watery or has blood in it;


• pale or yellowed skin, dark colored urine, fever, confusion or weakness;


• easy bruising or bleeding;


• skin rash, bruising, severe tingling, numbness, pain, muscle weakness;


• agitation, confusion, unusual thoughts or behavior, seizure (convulsions);


• nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or


• severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Less serious side effects may include:

• mild diarrhea, gas, stomach pain;


• nausea or vomiting;


• headache;


• skin rash or itching;


• white patches in your mouth or throat; or


• vaginal yeast infection (itching or discharge).