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About Product
Clozapine 100 mg tablets
What clozapine is used for:
Clozapine is used to treat people with schizophrenia in whom other medicines have not worked. Clozapine is also used to treat severe disturbances in the thoughts, emotions and behavior of people with Parkinson’s disease in whom other medicines have not worked.
Do not use clozapine if you:
• are allergic (hypersensitive) to clozapine or any of the other ingredients of Clozapine
• are not able to have regular blood tests.
• have ever been told you have a low white blood cell count (e.g. leucopenia or agranulocytosis), especially if this was caused by medicines. This does not apply if you have had low white blood cell count caused by previous chemotherapy.
• had to stop using Clozapine previously because of severe side effects (e.g. agranulocytosis or heart problems).
• are being or have been treated with long-acting depot injections of antipsychotics.
• suffer from bone marrow disease or have ever suffered from bone marrow disease.
• suffer from uncontrolled epilepsy (seizures or fits).
• have an acute mental illness caused by alcohol or drugs (e.g. narcotics).
• suffer from reduced consciousness and severe drowsiness.
• suffer from circulatory collapse which may occur as a result of severe shock.
• suffer from any severe kidney disease.
• suffer from myocarditis (an inflammation of the heart muscle).
• suffer from any other severe heart disease.
• have symptoms of active liver disease such as jaundice (yellow coloring of the skin and eyes, feeling sick and loss of appetite).
• suffer from any other severe liver disease.
• suffer from paralytic ileus (your bowel does not work properly and you have severe constipation).
• use any medicine that stops your bone marrow from working properly.
• use any medicine that reduces the number of white cells in your blood
Warnings and precautions:
Tell your doctor if you have or ever had:
• blood clots or family history of blood clots, as medicines like these have been associated with formation of blood clots
• glaucoma (increased pressure in the eye)
• diabetes. Elevated (sometimes considerably) blood sugar levels, has occurred in patients with or without diabetes mellitus in their medical history
• prostate problems or difficulty in urinating
• any heart, kidney or liver disease
• chronic constipation or if you are taking medicines which cause constipation (such as anticholinergics)
• galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption
• controlled epilepsy
• large intestine diseases
• abdominal surgery
• a heart disease or family history of abnormal conduction in the heart called “prolongation of the QT interval”
• a risk for having a stroke, for example if you have high blood pressure, cardiovascular problems or blood vessel problems in the brain
Possible side effects:
Stop using the product and seek immediate medical attention if you develop throat tightness or swelling of the eyes, face, lips or tongue, feel faint, or have difficulty breathing. Stop using the product if you develop hives or itching of the face or body.
Other medicines and clozapine:
Do not take Clozapine together with medicines that stop the bone marrow from working properly and/or decrease the number of blood cells produced by the body
How to use clozapine:
Treatment of schizophrenia: The effective daily dose is usually between 200 mg and 450 mg, divided into several single doses per day. Some people might need more. A daily dose of up to 900 mg is allowed.
Treatment of severe thought disturbances in patients with Parkinson’s disease: The effective daily dose is usually between 25 mg and 37.5 mg, taken as one dose in the evening. Doses of 50 mg per day should only be exceeded in exceptional cases. The maximum daily dose is 100 mg.
How to store clozapine:
Keep this medicine out of the sight and reach of children.
Do not use Clozapine after the expiry date which is stated on the blister/bottle and the carton. The expiry date refers to the last day of that month.
This medicinal product does not require any special storage conditions.
Do not throw away any medicines via wastewater or household waste.
Product Details:
- Manufacturer: Leponex
- Quantity: 50 Tablets
Prescription required to order this medicine