Leponex 25 mg Tablet 50pcs

Clozapine 25 mg tablets

 

What clozapine is used for :

Clozapine is used to treat people with
schizophrenia in whom other medicines have not worked. Clozapine is also used
to treat severe disturbances in the thoughts, emotions and behavior of people
with Parkinson’s disease in whom other medicines have not worked.

  

Do not use clozapine if you :

•        are
allergic (hypersensitive) to clozapine or any of the other ingredients of
Clozapine

•        are
not able to have regular blood tests. 

•        have
ever been told you have a low white blood cell count (e.g. leucopenia or agranulocytosis),
especially if this was caused by medicines. This does not apply if you have had
low white blood cell count caused by previous chemotherapy. 

•        had
to stop using Clozapine previously because of severe side effects (e.g.
agranulocytosis or heart problems). 

•        are
being or have been treated with long-acting depot injections of
antipsychotics. 

•        suffer
from bone marrow disease or have ever suffered from bone marrow disease. 

•        suffer
from uncontrolled epilepsy (seizures or fits). 

•        have
an acute mental illness caused by alcohol or drugs (e.g. narcotics). 

•        suffer
from reduced consciousness and severe drowsiness. 

•        suffer
from circulatory collapse which may occur as a result of severe shock. 

•        suffer
from any severe kidney disease. 

•        suffer
from myocarditis (an inflammation of the heart muscle). 

•        suffer
from any other severe heart disease. 

•        have
symptoms of active liver disease such as jaundice (yellow coloring of the skin
and eyes, feeling sick and loss of appetite). 

•        suffer
from any other severe liver disease. 

•        suffer
from paralytic ileus (your bowel does not work properly and you have severe
constipation). 

•        use
any medicine that stops your bone marrow from working properly. 

•        use
any medicine that reduces the number of white cells in your blood

 

Warnings and precautions :

Tell your doctor if you have or ever had:

•        blood
clots or family history of blood clots, as medicines like these have been
associated with formation of blood clots

•        glaucoma
(increased pressure in the eye)

•        diabetes.
Elevated (sometimes considerably) blood sugar levels, has occurred in patients
with or without diabetes mellitus in their medical history 

•        prostate
problems or difficulty in urinating

•        any
heart, kidney or liver disease

•        chronic
constipation or if you are taking medicines which cause constipation (such as
anticholinergics)

•        galactose
intolerance, Lapp lactase deficiency or glucose-galactose malabsorption

•        controlled
epilepsy

•        large
intestine diseases

•        abdominal
surgery

•        a
heart disease or family history of abnormal conduction in the heart called
“prolongation of the QT interval”

•        a
risk for having a stroke, for example if you have high blood pressure,
cardiovascular problems or blood vessel problems in the brain

 

Possible side effects :

Stop using the product and seek immediate
medical attention if you develop throat tightness or swelling of the eyes,
face, lips or tongue, feel faint, or have difficulty breathing. Stop using the
product if you develop hives or itching of the face or body. 

 

Other medicines and clozapine :

Do not take Clozapine together with medicines
that stop the bone marrow from working properly and/or decrease the number of
blood cells produced by the body

  

How to use clozapine :

Treatment of schizophrenia: The effective daily
dose is usually between 200 mg and 450 mg, divided into several single doses
per day. Some people might need more. A daily dose of up to 900 mg is allowed.

Treatment of severe thought disturbances in
patients with Parkinson’s disease: The effective daily dose is usually between
25 mg and 37.5 mg, taken as one dose in the evening. Doses of 50 mg per day
should only be exceeded in exceptional cases. The maximum daily dose is 100
mg. 

  

How to store clozapine :

Keep this medicine out of the sight and reach of
children. 

Do not use Clozapine after the expiry date which
is stated on the blister/bottle and the carton. The expiry date refers to the
last day of that month. 

This medicinal product does not require any
special storage conditions. 

Do not throw away any medicines via wastewater
or household waste.