Hydrochlorothiazide & Amiloride hydrochloride 50 mg/5 mg tablets

What Hydrochlorothiazide & Amiloride hydrochloride is and what it is used for

Hydrochlorothiazide & Amiloride hydrochloride is used for:

• Heart failure.


• High blood pressure.


• Fluid retention caused by a liver disease called cirrhosis.

Do not take Hydrochlorothiazide & Amiloride hydrochloride tablets

• If you are allergic to hydrochlorothiazide and amiloride hydrochloride or any of the other Ingredients of this medicine.


• If you have diabetes (a high blood sugar level).


• If you have been told by your doctor you have high levels of urea, creatinine, potassium or Calcium in your blood.


• If you are allergic to a type of antibiotic called sulfonamides, such as sulfamethoxazole.


• If you are allergic to acetazolamide which is a diuretic used to remove fluid from the body and to Treat high pressure in the eye (glaucoma), heart problems and sometimes fits or epilepsy.


• If you are allergic to any other thiazides water tablet (diuretic).


• If you are taking a potassium supplement or medicine containing potassium or you eat potassium-Rich foods.


• If you suffer from kidney or liver disease.

Warnings and precautions

Talk to your doctor or pharmacist before taking Hydrochlorothiazide & Amiloride hydrochloride if:

• You have been told by your doctor you have high levels of uric acid, cholesterol or triglycerides (a type of cholesterol) in your blood.


• You are taking digitalis such as digoxin - used for heart failure and abnormal heart beat.


• You are being given fluids by a tube inserted into one of your veins.


• You have recently suffered from severe vomiting or diarrhea.


• You have Systemic Lupus Erythematosus.


• You are elderly.


• You have gout.


• You have had skin cancer or if you develop an unexpected skin lesion during the treatment.

Possible side effects

Like all medicines, Hydrochlorothiazide & Amiloride hydrochloride can cause side effects, although not everybody gets them. The following side effects may happen with this medicine:

• Stop taking Hydrochlorothiazide & Amiloride hydrochloride and see a doctor straight away, if you Notice any of the following serious side effects that may occur.


• You may need urgent medical treatment:


• Allergic reactions - the signs may include inflamed blood vessels, difficulties breathing or swallowing, collapse, redness, blisters, peeling skin, muscle pains, chills, a general feeling of being unwell, ulcers in your mouth, eyes or genitals.


• Irregular heart beat of your heart that can lead to fainting and dizziness, palpitations


• Fast heart beat, chest pains (angina).


• Bleeding from your gut - signs may include blood in your feces or a darker color of feces.


• Liver problems such as jaundice - signs may include yellowing of the skin and/or whites of the Eyes.

Other medicines and Hydrochlorothiazide & Amiloride hydrochloride

• Tell your doctor or pharmacist if you are taking or have recently taken or might take any other medicines, including medicines obtained without a prescription.


• This includes herbal medicines.

It is important to tell your doctor or pharmacist if you take:

• Angiotensin converting enzyme inhibitors (ACE inhibitors) such as Enalapril used to treat high Blood pressure or heart problems.


• Angiotensin II receptor antagonists such as Losartan - used to treat high blood pressure or Diabetics with kidney damage.


• Other medicines for high blood pressure.


• Medicines for diabetes such as Insulin or Chlorpropamide.


• Lithium - used for depression.


• Non-steroidal anti-inflammatory drugs (NSAIDs), such as aspirin or ibuprofen - used to reduce High temperature (fever), pain or for arthritis.


• Barbiturates - used to help you sleep or to reduce anxiety.


• Painkillers such as codeine, dihydrocodeine, dextropropoxyphene, diamorphine, morphine, Pentazocine and pethidine.


• Cholestyramine and colestipol - used to treat high cholesterol (hyperlipidemia).


• Steroids - used to treat lots of different conditions such as rheumatism, arthritis, allergic. Conditions, skin problems, asthma or a type of blood disorder.


• Ciclosporin - used for rheumatoid arthritis or to prevent rejection after a transplant.


• Non-depolarizing muscle relaxants such as tubocurarine.

How to take Hydrochlorothiazide & Amiloride hydrochloride:

• Always take this medicine exactly as your doctor has told you.


• Check with your doctor or pharmacist if you are not sure.


• You should take this medicine by mouth.


• The amount you take each day will depend on your Illness.


• The number of tablets to be taken will be on the label of your medicine.

The recommended doses are:

High blood pressure:

• The usual starting dose is half a tablet each day.


• Your doctor may change your dose to one tablet given each day.


• Your doctor may spread out the dose or give it as a single dose.

Heart failure:

• The usual starting dose is half a tablet each day.


• Your doctor may change your dose.


• You should not take more than two tablets in a day.

Fluid retention due to cirrhosis:

• The usual starting dose is one tablet each day.


• Your doctor may change your dose.


• You should not take more than two tablets in a day.

How to store Hydrochlorothiazide & Amiloride hydrochloride:

• Keep this medicine out of the sight and reach of children.


• Do not use the medicine after the expiry date which is stated on the carton after EXP.


• The expiry Date refers to the last day of that month.


• Store below 25°C. Protect from moisture.


• Do not throw away any medicines via wastewater or household waste.


• Ask your pharmacist how to throw away medicines you no longer use.


• These measures will help to protect the environment.