Product Description:

• Generic Name: esomeprazole


• Drug Classes: proton pump inhibitor

Uses

• Esomeprazole is used to treat heartburn and certain other conditions caused by too much acid in the stomach.

• Gastroesophageal reflux disease (GERD), where stomach acid backs up into your esophagus


• To treat or help prevent ulcers


• To treat or help prevent erosive esophagitis (EE)


• Other conditions where your stomach makes too much acid


• Treatment of Helicobacter pylori (H. pylori) infections


• Esomeprazole may also be used for other conditions as determined by your healthcare provider.

How does esomeprazole work (mechanism of action)?

• Esomeprazole works by reducing the amount of acid your stomach makes.

Side Effects

• Headache


• Diarrhea


• Nausea


• Gas


• Stomach pain


• Constipation


• Dry mouth


• There may be other side effects of esomeprazole that are not listed here.


• Contact your healthcare provider if you think you are having a side effect of a medicine.

Warnings and precautions:

• You should let your doctor know:


• You have had a stomach ulcer or stomach surgery in the past.


• You have been taking treatment continuously for reflux or heartburn for 4 or more weeks.


• You have jaundice (yellowing of skin or eyes) or severe liver problems.


• You have severe kidney problems.


• You are aged over 55 years and have new or recently changed reflux symptoms or need to take a non-prescription indigestion or heartburn remedy treatment every day.


• You have ever had a skin reaction after treatment with a medicine similar to Esomeprazole that reduces stomach acid.


• You are due to have an endoscopy or a urea breath test.


• You are due to have a specific blood test (Chromogranin A).

• Other medicines and Esomeprazole:


• Do not take this medicine if you are also taking a medicine containing nelfinavir (used to treat HIV infection).


• You should specifically tell your doctor or pharmacist if you are taking clopidogrel (used to prevent blood clots).


• Do not take this medicine with other medicines that limit the amount of acid produced in your stomach such as proton pump inhibitors (e.g. pantoprazole, lansoprazole, rabeprazole or omeprazole) or an H2 antagonist (e.g. ranitidine or famotidine)

How To Use:

• powder that is mixed into liquid and swallowed

Other medicines and Esomeprazole:

• Do not take this medicine if you are also taking a medicine containing nelfinavir (used to treat HIV infection).


• You should specifically tell your doctor or pharmacist if you are taking clopidogrel (used to prevent blood clots).


• Do not take this medicine with other medicines that limit the amount of acid produced in your stomach such as proton pump inhibitors (e.g. pantoprazole, lansoprazole, rabeprazole or omeprazole) or an H2 antagonist (e.g. ranitidine or famotidine)

Inform your doctor about the medicines you are taking, especially mention to you doctor if you are taking:

• Ketoconazole and itraconazole (used to treat infections caused by a fungus).


• Voriconazole (used to treat infections caused by a fungus) and clarithromycin (used to treat infections). Your doctor may adjust your dose of Esomeprazole if you also have severe liver problems and are treated for a long period of time.


• Erlotinib (used to treat cancer).


• Methotrexate (used to treat cancer and rheumatic disorders).


• Digoxin (used for heart problems).


• Atazanavir, saquinavir (used to treat HIV infection).


• Citalopram, imipramine or clomipramine (used to treat depression).


• Diazepam (used to treat anxiety, relax muscles or in epilepsy).


• Phenytoin (used to treat epilepsy).


• Medicines that are used to thin your blood, such as warfarin. Your doctor may need to monitor you when you start or stop taking Esomeprazole.


• Cilostazol (used to treat intermittent claudication – a condition where poor blood supply to the leg muscles causes pain and difficulty in walking).


• Cisapride (used for indigestion and heartburn).


• Rifampicin (used to treat tuberculosis).Tacrolimus (in cases of organ transplantation).


• John’s wort (Hypericum perforatum) (used to treat depression). risk of a lowered threshold for seizures.

How should I store esomeprazole?

• Esomeprazole should be stored at room temperature, between (20 C to 25 C).


• It can be exposed to temperatures between (15 C to 30 C), for shorter periods of time, such as when transporting it.


• Store in a cool, dry place.

What should I do if I miss a dose of esomeprazole?

• If you miss a dose, take it as soon as you remember.


• If it is almost time for your next dose, skip the missed dose and only take the next dose. Do not take double or extra doses.