This medication is dispensed with a valid prescription only.

Product Description

Insulin Glargine + Lixisenatide 100 units/ml + 33 micrograms/ml Solution for Injection in a Pre-filled Pen

What is Insulin Glargine + Lixisenatide used for?

Insulin Glargine + Lixisenatide is used to improve blood sugar levels in adult patients with Type 2 diabetes.

It contains two active substances that help your body control blood sugar:

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  Insulin Glargine – a long-acting basal insulin that lowers blood sugar levels.

  
  


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  Lixisenatide – a GLP-1 receptor agonist that helps your body produce more insulin during meals and reduces the amount of sugar produced by the body.

  
  

Insulin Glargine + Lixisenatide is used together with oral antidiabetic medicines (such as metformin, pioglitazone, and sulfonylureas). It is prescribed when these medicines alone, or in combination with GLP-1 therapy or basal insulin, are not sufficient to control blood glucose levels.

Do not use Insulin Glargine + Lixisenatide:

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  If you are allergic to insulin glargine, lixisenatide, or any of the other ingredients of this medicine.

  
  

Warnings and Precautions

Talk to your doctor before using Insulin Glargine + Lixisenatide if:

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  You are taking other medicines for diabetes.

  
  


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  Do not use it if you have Type 1 diabetes or diabetic ketoacidosis.

  
  


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  Do not use in patients under 18 years of age.

  
  


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  It is not recommended for patients with inflammatory bowel disease or delayed gastric emptying.

  
  


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  If you have eye problems.

  
  


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  If you have or previously had thyroid disease.

  
  


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  If you experience severe abdominal pain that does not go away, as this may indicate pancreatitis.

  
  


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  If you experience dehydration (fluid loss), especially if you have nausea, vomiting, or diarrhea.

  
  

Possible Side Effects

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  This medicine is administered as a subcutaneous injection (under the skin). Do not inject into a vein or muscle.

  
  


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  The best injection sites are the front of the thighs, upper arms, or abdomen.

  
  


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  Rotate injection sites daily to reduce the risk of lumps or skin changes.

  
  


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  Always use a new needle for each injection. Reusing needles may increase the risk of blockage and inaccurate dosing. Dispose of the needle safely after each use.

  
  

Other Medicines and Insulin Glargine + Lixisenatide

Tell your doctor if you are taking or have recently taken any other medicines, including non-prescription medicines, especially medications used for:

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  Contraception

  
  


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  Pain management

  
  


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  Hormone replacement

  
  


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  Diabetes

  
  


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  High blood pressure

  
  


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  Asthma

  
  


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  Depression

  
  


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  Autoimmune diseases

  
  


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  Infections

  
  

How to Use Insulin Glargine + Lixisenatide

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  Your dose is given as “dose steps,” shown on the pen’s dose counter.

  
  


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  Use once daily, preferably at the same time each day.

  
  


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  It is administered as a subcutaneous injection only.

  
  


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  Rotate injection sites daily.

  
  


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  Always use a new needle and dispose of it safely after each use.

  
  

Storage Instructions

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  Keep out of the sight and reach of children.

  
  


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  Do not use after the expiry date stated on the pen or carton.

  
  


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  Before opening: Store in a refrigerator (2°C–8°C). Do not freeze.

  
  


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  During use: Can be kept at room temperature (below 30°C) or refrigerated for up to 21 days. Discard after 21 days from first use.

  
  


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  Always keep the pen cap on when not in use to protect from light.

  
  


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  Do not dispose of medicines in wastewater or household waste.