This medication is dispensed with a valid prescription only

Insulin Degludec + Liraglutide 100 units/ml + 3.6 mg/ml Solution for Injection in a Pre-filled Pen

What is Insulin Degludec + Liraglutide and what is it used for?

Insulin Degludec + Liraglutide is used to improve blood sugar levels in adult patients with Type 2 diabetes.

It contains two active substances that help your body control blood glucose levels:

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  Insulin Degludec – a long-acting basal insulin that lowers blood sugar levels.

  
  


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  Liraglutide – a GLP-1 analogue that helps your body produce more insulin during meals and reduces the amount of sugar produced by the body.

  
  

Insulin Degludec + Liraglutide is used together with oral antidiabetic medicines (such as metformin, pioglitazone, and sulfonylureas). It is prescribed when these medicines, used alone or with GLP-1 therapy or basal insulin, are not sufficient to control blood glucose levels.

Do not use Insulin Degludec + Liraglutide:

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  If you are allergic to insulin degludec, liraglutide, or any of the other ingredients of this medicine.

  
  

Warnings and Precautions

Talk to your doctor before using Insulin Degludec + Liraglutide if:

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  You are taking other medicines for diabetes.

  
  


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  Do not use this medicine if you have Type 1 diabetes or diabetic ketoacidosis.

  
  


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  Do not use in patients under 18 years of age.

  
  


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  It is not recommended for patients with inflammatory bowel disease or delayed gastric emptying.

  
  


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  If you have eye problems.

  
  


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  If you have or previously had thyroid disease.

  
  


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  If you experience severe abdominal pain that does not go away, as this may be a sign of pancreatitis.

  
  


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  If you experience dehydration (fluid loss) due to nausea, vomiting, or diarrhea; it is important to drink plenty of fluids.

  
  

Possible Side Effects

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  This medicine is administered as a subcutaneous injection (under the skin). Do not inject into a vein or muscle.

  
  


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  The best injection sites are the front of the thighs, upper arms, or abdomen.

  
  


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  Rotate injection sites daily to reduce the risk of lumps or skin changes.

  
  


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  Always use a new needle for each injection. Reusing needles may increase the risk of blockage and inaccurate dosing. Dispose of the needle safely after each use.

  
  

Other Medicines and Insulin Degludec + Liraglutide

Tell your doctor if you are taking or have recently taken any other medicines, including over-the-counter medicines, especially medicines used for:

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  Contraception

  
  


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  Pain relief

  
  


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  Hormone replacement

  
  


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  Diabetes

  
  


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  High blood pressure

  
  


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  Asthma

  
  


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  Depression

  
  


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  Autoimmune diseases

  
  


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  Infections

  
  

How to Use Insulin Degludec + Liraglutide

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  Your dose is given as “dose steps,” indicated on the pen’s dose counter.

  
  


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  Use once daily, preferably at the same time each day.

  
  


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  One dose step contains 1 unit of insulin degludec and 0.036 mg of liraglutide.

  
  


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  The maximum daily dose is 50 dose steps (50 units of insulin degludec and 1.8 mg of liraglutide).

  
  


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  It is administered as a subcutaneous injection only.

  
  


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  Rotate injection sites daily.

  
  


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  Always use a new needle for each injection and dispose of it safely after use.

  
  

Storage Instructions

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  Keep this medicine out of the sight and reach of children.

  
  


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  Do not use after the expiry date shown on the pen label and carton.

  
  


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  Before opening: Store in a refrigerator (2°C–8°C). Do not freeze.

  
  


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  During use: Can be stored at room temperature (below 30°C) or refrigerated (2°C–8°C) for up to 21 days. Discard after 21 days from first use.

  
  


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  Keep the pen cap on when not in use to protect it from light.

  
  


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  Do not dispose of medicines via wastewater or household waste.